Many doctors have been offered on the Internet and presumably effective treatment options for selecting the gender / sex selection. The truth is, however, that the real work of the options are pretty limited.
Specifically, there are only two options, as studies have proven effective: one is IVF combined with PGD / PGS, which can determine the sex of each embryo created by in vitro fertilization, before the embryos are transferred into the uterus . Another option, known as sperm sorting is based on the fact that the male determines the sex of the child or by contributing an X or Y chromosome (the female always contributes an X) through his sperm. Every sperm is either X or Y-bearing.
The concept of sperm sorting is based on the enrichment of the seed, whether they bear X or Y. Many of the sperm sorting techniques have been proposed in recent years (for details see below), but only one has never been shown, in fact, be able to affect the typical ratio of 50 / 50 X sperm and this is a patented technique called MicroSort ®. After completing a year of many trials in length, in which our center has participated, this technique is currently under review by the Food and Drug Administration (FDA), and therefore is not clinically available for U.S. elective gender selection. The FDA has extended the use of the test for married couples with established sex-linked diseases. Once again available for sex selection to choose from, our place in this regard.
Let's look at a range of procedures offered to the market a few more details:
Sperm sorting
As mentioned earlier, this method is based on the long-established principle that the genetic contribution of the male partner determines the sex of offspring is a contribution by X-bearing or Y-bearing sperm in the fertilization process. Women with XX sex chromosomes, of course, always contribute an X chromosome Therefore, based on the contribution of male embryos resulting either XY (male) or XX (female).
We recognize the portion of the male sex selection, a series of successful claims history was made, based on the presumed ability to separate X-bearing sperm from Y-bearing sperm. Unfortunately, until recently, no one could prove that their method actually worked to improve the odds towards the opposite sex or the other. MicroSort ® was the first selection procedure of sperm never been shown to be effective in changing the 50/50 ratio of X and Y-bearing sperm. Technique is based on the labeling of sperm with a fluorescent marker, which can then take the so-called fluorescent cell sorter.
It is our perception of the Centre for sex selection, or micro black ® is the sperm sorting never shown to have a significant effect on the sex ratio. Based on births after treatment, the data released by micro ® black study suggests that the segregation of women will be about 90% success rate, while the sorting of the success of males is about 85%. In other words, the kind of women still result in a male birth in about 10% of cases, and sorting of about 15% of males will result in the delivery of a woman.
In vitro fertilization (IVF) and preimplantation genetic diagnosis (PGD)
Unlike sorting sperm, this technique is the so-called post-fertilization techniques. This is the ethical and / or religious, can be an important difference for some patients. Here are the first items produced by fertilization of eggs, sperm from a partner of the woman (IVF). Then, the embryos are tested for their gender / sex.
This means that the technique is almost always produce embryos of the desired sex, then raise the issue of ethics and practice what to do with these embryos. The options are (1) freeze (freeze) for future use, (2) to give (usually anonymously) for infertile couples, (3) to donate to HRC for research purposes, or (4) ask the Human Rights Council that an ethical manner.
The process involves the woman undergoing an IVF cycle. Embryos generated in this cycle of IVF undergo PGD / PGS on the third day after fertilization, when it reached 6.8 overall stage of the cell. At this point, one of these cells was extracted from each embryo microsurgery and their chromosomes (including chromosome X and Y) are analyzed, allowing us to determine if the embryo is male or female. Once each embryo is defined as a genre, only embryos of the desired sex are transferred to the uterus of the woman, almost a guarantee of pregnancy in the desired gender. This technique is much more accurate than the selection of sperm in predicting the sex of the pregnancy.
The use of IVF and PGD for gender / sex selection has other advantages and disadvantages. An added benefit is clear that at the same time that the review of each embryo sex, other chromosomes also checked. The most common chromosomal abnormalities in human embryos, such as Down syndrome can be excluded with high accuracy. A possible disadvantage is that the micromanipulation of embryos may slightly reduce its chances of implantation in the uterus. But the evidence so far suggests that the risk of malformations is not increased by the selection of sex with IVF and PGD.
Before deciding to pursue this method of sex selection, we strongly recommend further discussion of the advantages and disadvantages of the techniques available from your doctor. You should also consider the costs for each of these options with your medical staff. The final choice is ultimately both a medical and ethical decision making.
We also want to familiarize you with the option of other types of choices offered. Since we do not consider "effective", we can not recommend them. Here is a list of options for treatment of sex selection can be found on the web. We list these other techniques to provide accurate information about them. Already submitted to you:
IVF / PGD + IVF / PGD method
MicroSort Method ® *
Other techniques are not recommended:
Ericsson Method
Whelan method
Shettles Method
Sex selection kits
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